This hotel is located just south of Hamburg city centre, a 15-minute walk from Hamburg Main Station and the Mönckebergstraße shopping street. It offers air-conditioned rooms with a flat-screen TV. City Hotel Hamburg Mitte offers modern rooms with wooden floors. All rooms include a flat-screen TV, desk and private bathroom, and some have harbour views. A breakfast buffet is available in the bright and warmly furnished breakfast room. The City Hotel Hamburg Mitte is 10 metres from Lippeltstraße bus stop and 500 metres from Hammerbrook City Süd S-Bahn Train Station. Private parking spaces can be booked in the hotel's own garage. The Port of Hamburg and the Reeperbahn nightlife and theatre district are 4 km away.

Guests receive 30 minutes' free Wi-Fi access in public areas of the hotel.